SARS-CoV-2 Cytopathic Effect detection

SARS-CoV-2, a novel coronavirus strain, has spread to almost every country in the world and thus become a major public health concern. Researchers all over the world are trying their best to improve the current situation in different methods. Cytopathic Effect (CPE) assay is one of the antiviral tests that may help with discovering more information about SARS-CoV-2. As a socially responsible company focused on antiviral research, Creative Biolabs has been committed to SARS-CoV-2 and relative studies since it broke out. With advanced technology and mature researchers, we provide global clients with reliable CPE assay services to promote the study of SARS-CoV-2.

Introduction of CPE

Various pathological cell alterations triggered by eukaryotic viruses are referred to as the CPE. Due to viral infections, the structure of the host cell changes and sometimes results in cell lysis. Common CPE includes rounding, detachment (plaques), clumping, ballooning (giant cell), fusion (syncytium formation), and inclusion body formation. The formation of inclusion bodies or syncytia induced by CPE can help with diagnosing viral infections. Therefore, by CPE, viral proliferation could be estimated through observable changes in cultured cells under a light microscope. In summary, CPE is a feasible scheme for viral isolation and identification.

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